Research

September 2007

September 13, 2007

Markov processes in single molecule fluorescence

Posted by David Talaga

Markov Review Final

David S. Talaga, Current Opinion in Colloid & Interface Science 12:6 (2007) 285-296

This article examines the current status of Markov processes in single molecule fluorescence. For molecular dynamics to be described by a Markov process, the Markov process must include all states involved in the dynamics and the FPT distributions out of those states must be describable by a simple exponential law. The observation of non-exponential first-passage time distributions or other evidence of non-Markovian dynamics is common in single molecule studies and offers an opportunity to expand the Markov model to include new dynamics or states that improve understanding of the system.
Link to published version